Jorvik: a membrane-containing phage that will likely found a new family within Vinavirales
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14310%2F23%3A00131849" target="_blank" >RIV/00216224:14310/23:00131849 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1016/j.isci.2023.108104" target="_blank" >https://doi.org/10.1016/j.isci.2023.108104</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.isci.2023.108104" target="_blank" >10.1016/j.isci.2023.108104</a>
Alternative languages
Result language
angličtina
Original language name
Jorvik: a membrane-containing phage that will likely found a new family within Vinavirales
Original language description
Although membrane-containing dsDNA bacterial viruses are some of the most prevalent predators in aquatic environments, we know little about how they function due to their intractability in the laboratory. Here, we have identified and thoroughly characterized a new type of membrane-containing bacteriophage, Jorvik, that infects the freshwater mixotrophic model bacterium Rhodobacter capsulatus. Jorvik is extremely virulent, can persist in the host integrated into the RuBisCo operon and encodes two experimentally verified cell wall hydrolases. Jorvik-like prophages are abundant in the genomes of alpha-proteobacteria, are distantly related to known viruses of the class Tectiliviricetes, and we propose they should be classified as a new family. Crucially, we demonstrate how widely used phage manipulation methods should be adjusted to prevent loss of virus infectivity. Our thorough characterization of environmental phage Jorvik provides important experimental insights about phage diversity and interactions in microbial communities that are often unexplored in common metagenomic analyses.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10607 - Virology
Result continuities
Project
<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
iScience
ISSN
2589-0042
e-ISSN
2589-0042
Volume of the periodical
26
Issue of the periodical within the volume
11
Country of publishing house
US - UNITED STATES
Number of pages
19
Pages from-to
„108104“
UT code for WoS article
001112930800001
EID of the result in the Scopus database
2-s2.0-85173700862