Visibility-Based Approach to Surface Detection of Tunnels in Proteins
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14330%2F15%3A00080777" target="_blank" >RIV/00216224:14330/15:00080777 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1145/2788539.2788548" target="_blank" >http://dx.doi.org/10.1145/2788539.2788548</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1145/2788539.2788548" target="_blank" >10.1145/2788539.2788548</a>
Alternative languages
Result language
angličtina
Original language name
Visibility-Based Approach to Surface Detection of Tunnels in Proteins
Original language description
Structural properties of proteins substantially influence their reactivity. Thus, the presence of pathways serving for transportation of a small molecule to the protein active site is crucial. These pathways, called tunnels, are defined by their surroundings --- tunnel lining amino acids (or residues). In consequence, studying these amino acids and their properties is tightly connected with protein reactivity. The set of tunnel lining amino acids detected for a given tunnel can differ with respect to selected algorithm for their computation. The criteria for evaluating their biochemical relevance are different as well, as they can depend on various physico-chemical properties. In this paper we firstly present a novel approach to the detection of tunnellining amino acids. This approach is more robust in comparison with the existing methods. It is based on the visibility of atoms of the amino acids from the tunnel surface, often derived from the Voronoi diagram.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
IN - Informatics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP202%2F10%2F1435" target="_blank" >GAP202/10/1435: Analysis and Visualization of Protein Structures</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
31st Proceedings of Spring Conference on Computer Graphics
ISBN
9781450336932
ISSN
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e-ISSN
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Number of pages
8
Pages from-to
85-92
Publisher name
Comenius University
Place of publication
Bratislava, Slovakia
Event location
Smolenice Castle
Event date
Apr 22, 2015
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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