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Resolving chromatin organization in chronic lymphocytic leukemia.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216224%3A14740%2F23%3A00132766" target="_blank" >RIV/00216224:14740/23:00132766 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.embl.org/about/info/course-and-conference-office/events/can23-01/" target="_blank" >https://www.embl.org/about/info/course-and-conference-office/events/can23-01/</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Resolving chromatin organization in chronic lymphocytic leukemia.

  • Original language description

    The spatial chromatin organization has been recognized as essential for fundamental cell processes. Disruption of its hierarchical structure can be caused by chromosomal rearrangements, which, especially in cancer cells, lead to aberrant molecular signaling. We aim to study altered genome structure in chronic lymphocytic leukemia (CLL), the most common type of leukemia in adults. We are particularly interested in the analysis of long-distance chromatin interactions and the formation of topologically associated domains (TADs), which might play a role in CLL pathogenesis.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

  • OECD FORD branch

    30204 - Oncology

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů