Short-term stability of biomarkers of oxidative stress and antioxidant status in human serum

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216275%3A25310%2F13%3A39896517" target="_blank" >RIV/00216275:25310/13:39896517 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1155/4174" target="_blank" >http://dx.doi.org/10.1155/4174</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1155/4174" target="_blank" >10.1155/4174</a>

Result language

angličtina

Original language name

Short-term stability of biomarkers of oxidative stress and antioxidant status in human serum

Original language description

The oxidation and antioxidant status of serum are often determined in serum samples which have been frozen for some time. The oxidative stress process is prone to fast alterations in the sample because of the possible instability of the reactants. Here one oxidation assay (ROM) and three antioxidant assays (FRAP, TAS, and BAP) have been tested on their performance and stability at short-time storage. The most commonly used temperatures for storage and handling of serum samples (+4 and +20?C) were selected. In three short-term studies in which the storage time varied between 3 and 48 hrs the performance of these assays were tested on human serum samples. The general conclusion is that most assays performed well and gave stable results during 2 days of storage of the samples at both temperatures. Only the FRAP and TAS assays showed a small deviation at some storage conditions. In conclusion, handling of serum samples at +4 and +20?C during short-time periods did not affect the quality an

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

ISRN Biomarkers

ISSN

2314-6265

e-ISSN

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Volume of the periodical

2013

Issue of the periodical within the volume

2013

Country of publishing house

EG - EGYPT

Number of pages

5

Pages from-to

1-5

UT code for WoS article

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EID of the result in the Scopus database

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