Effect of the selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00216305%3A26620%2F17%3APU128372" target="_blank" >RIV/00216305:26620/17:PU128372 - isvavai.cz</a>

Alternative codes found

RIV/62156489:43210/17:43912630

Result on the web

<a href="https://mendelnet.cz/artkey/mnt-201701-0103_Effect-of-the-selected-phenolic-and-flavonoid-compounds-of-black-pepper-and-caraway-seeds-on-prostate-cells.php?back=/magno/mnt/2017/mn1.php?secid=4" target="_blank" >https://mendelnet.cz/artkey/mnt-201701-0103_Effect-of-the-selected-phenolic-and-flavonoid-compounds-of-black-pepper-and-caraway-seeds-on-prostate-cells.php?back=/magno/mnt/2017/mn1.php?secid=4</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Effect of the selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells

Original language description

In this study, the effect of selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells (PNT1A, 22RV1 and PC3) was observed. Synthetic standards of 3,4-dihydroxybenzaldehyde and naringenin chalcone, identified previously by HPLC-MS in black pepper seeds extracts, and neochlorogenic acid and apigenin, identified in caraway seeds extracts, were applied. For the evaluation of the potential inhibitory effect of selected compounds on PNT1A, 22RV1 and PC3 cells, the clonogenic assay and the microscopic observation of cells were done. The results of clonogenic assay showed that phenolic compounds had the strongest inhibitory effect on 22RV1 and PC3 cells, while the flavonoid compounds had the strongest inhibitory effect on PNT1A cells.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

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OECD FORD branch

30107 - Medicinal chemistry

Project

<a href="/en/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

MendelNet 2017

ISBN

978-80-7509-529-9

ISSN

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e-ISSN

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Number of pages

5

Pages from-to

900-904

Publisher name

Mendel University in Brno

Place of publication

Neuveden

Event location

Brno

Event date

Nov 8, 2017

Type of event by nationality

CST - Celostátní akce

UT code for WoS article

000440194500161