Effect of the selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F17%3A43912630" target="_blank" >RIV/62156489:43210/17:43912630 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26620/17:PU128372
Result on the web
<a href="https://mnet.mendelu.cz/mendelnet2017/mnet_2017_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2017/mnet_2017_full.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Effect of the selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells
Original language description
In this study, the effect of selected phenolic and flavonoid compounds of black pepper and caraway seeds on prostate cells (PNT1A, 22RV1 and PC3) was observed. Synthetic standards of 3,4-dihydroxybenzaldehyde and naringenin chalcone, identified previously by HPLC-MS in black pepper seeds extracts, and neochlorogenic acid and apigenin, identified in caraway seeds extracts, were applied. For the evaluation of the potential inhibitory effect of selected compounds on PNT1A, 22RV1 and PC3 cells, the clonogenic assay and the microscopic observation of cells were done. The results of clonogenic assay showed that phenolic compounds had the strongest inhibitory effect on 22RV1 and PC3 cells, while the flavonoid compounds had the strongest inhibitory effect on PNT1A cells.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
30107 - Medicinal chemistry
Result continuities
Project
<a href="/en/project/LQ1601" target="_blank" >LQ1601: CEITEC 2020</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
MendelNet 2017: Proceedings of International PhD Students Conference
ISBN
978-80-7509-529-9
ISSN
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e-ISSN
neuvedeno
Number of pages
5
Pages from-to
900-904
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Nov 8, 2017
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000440194500161