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In vitro digestion and characterization of selenized Saccharomyces cerevisiae, Pichia fermentans and probiotic Saccharomyces boulardii

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F26722861%3A_____%2F24%3AN0000003" target="_blank" >RIV/26722861:_____/24:N0000003 - isvavai.cz</a>

  • Alternative codes found

    RIV/60460709:41210/24:98452 RIV/60461373:22340/24:43928421

  • Result on the web

    <a href="https://doi.org/10.1016/j.jtemb.2024.127402" target="_blank" >https://doi.org/10.1016/j.jtemb.2024.127402</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.jtemb.2024.127402" target="_blank" >10.1016/j.jtemb.2024.127402</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    In vitro digestion and characterization of selenized Saccharomyces cerevisiae, Pichia fermentans and probiotic Saccharomyces boulardii

  • Original language description

    Background and objective: Yeasts have the remarkable capability to transform and integrate inorganic selenium into their cellular structures, thereby enhancing its bioavailability and reducing its toxicity. In recent years, yeasts have attracted attention as potential alternative sources of protein. Methods: This study explores the selenium accumulation potential of two less explored yeast strains, namely the probiotic Saccharomyces boulardii CCDM 2020 and Pichia fermentas CCDM 2012, in comparison to the extensively studied Saccharomyces cerevisiae CCDM 272. Our investigation encompassed diverse stress conditions. Subsequently, the selenized yeasts were subjected to an INFOGEST gastrointestinal model. The adherence and hydrophobicity were determined with undigested cells Results: Stress conditions had an important role in influencing the quantity and size of selenium nanoparticles (SeNPs) generated by the tested yeasts. Remarkably, SeMet synthesis was limited to Pichia fermentas CCDM 2012 and S. boulardii CCDM 2020, with S. cerevisiae CCDM 272 not displaying SeMet production at all. Throughout the simulated gastrointestinal digestion, the most substantial release of SeCys2, SeMet, and SeNPs from the selenized yeasts occurred during the intestinal phase. Notably, exception was found in strain CCDM 272, where the majority of particles were released during the oral phase. Conclusion: The utilization of both traditional and non-traditional selenized yeast types, harnessed for their noted functional attributes, holds potential for expanding the range of products available while enhancing their nutritional value and health benefits

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    40401 - Agricultural biotechnology and food biotechnology

Result continuities

  • Project

    <a href="/en/project/LM2023064" target="_blank" >LM2023064: Infrastructure for Promoting Metrology in Food and Nutrition in the Czech Republic</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2024

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Trace Elements in Medicine and Biology

  • ISSN

    0946-672X

  • e-ISSN

  • Volume of the periodical

    83

  • Issue of the periodical within the volume

    May 2024

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    12

  • Pages from-to

    127402

  • UT code for WoS article

    001180369000001

  • EID of the result in the Scopus database

    2-s2.0-85184078575