Uniaxial tensile testing device for measuring mechanical properties of biological tissue with stress-relaxation test under a confocal microscope

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13420%2F18%3A43894150" target="_blank" >RIV/44555601:13420/18:43894150 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11510/18:10382591

Result on the web

<a href="http://dx.doi.org/10.21062/ujep/180.2018/a/1213-2489/MT/18/5/866" target="_blank" >http://dx.doi.org/10.21062/ujep/180.2018/a/1213-2489/MT/18/5/866</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.21062/ujep/180.2018/a/1213-2489/MT/18/5/866" target="_blank" >10.21062/ujep/180.2018/a/1213-2489/MT/18/5/866</a>

Result language

angličtina

Original language name

Uniaxial tensile testing device for measuring mechanical properties of biological tissue with stress-relaxation test under a confocal microscope

Original language description

Biological soft tissue is a non-linear and viscoelastic material and its mechanical properties can greatly affect qual-ity of life. Many external mechanical factors can alter the tissue, for example the tissue of talipes equinovarus congenitus, also known as clubfoot, which is the most frequent congenital deformity affecting lower extremities with pathological changes of connective tissue. In clubfoot, the presence of disc-like mass of fibrous tissue, resembling intervertebral disc tissue, is described to be between the medial malleolus and the medial side of the navicular bone. The clubfoot tissue is often referred to be stiffer or rigid by clinicians, or it is referred to as contracted and less contracted tissue, however relevant evidence about mechanical properties is missing. Therefore, the description &quot;disc-like&quot; is informing only about relative mechanical properties of clubfoot tissue. We aim to prepare methodical approach to quantify mechanical properties of biological tissue with uniaxial tensile stress-relaxation test, in order to help clinicians and scientist to identify precisely the mechanical properties of normal and pathological tissue and their structural behaviour during mechanical testing. In this study, we test and tune the uniaxial tensile stress-relaxation test on biological tissue with high content of connective tissue such as collagen. The model tissue is porcine pericardium. The tissue has clear collagen fibres aligning parallel to the force applied. Modulus of elasticity measured here is comparable to other studies.

Czech name

—

Czech description

—

Type

J_SC - Article in a specialist periodical, which is included in the SCOPUS database

CEP classification

—

OECD FORD branch

20301 - Mechanical engineering

Project

<a href="/en/project/LM2015062" target="_blank" >LM2015062: National Infrastructure for Biological and Medical Imaging</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Manufacturing Technology

ISSN

1213-2489

e-ISSN

—

Volume of the periodical

18

Issue of the periodical within the volume

5

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

7

Pages from-to

866-872

UT code for WoS article

—

EID of the result in the Scopus database

2-s2.0-85058047305