Dead-end (dnd) protein in fish – a review
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12520%2F21%3A43902545" target="_blank" >RIV/60076658:12520/21:43902545 - isvavai.cz</a>
Result on the web
<a href="https://doi.org/10.1007/s10695-018-0606-x" target="_blank" >https://doi.org/10.1007/s10695-018-0606-x</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10695-018-0606-x" target="_blank" >10.1007/s10695-018-0606-x</a>
Alternative languages
Result language
angličtina
Original language name
Dead-end (dnd) protein in fish – a review
Original language description
Dead end (dnd) is a germ plasm-specific maternal RNA discovered in zebrafish and then in other vertebrates. Dnd protein is essential for migration and motility of primordial germ cells (PGCs), only cells destined to transfer genetic information to offspring. PGCs arise far from somatic cells of developing gonads and they must migrate to their site of function. Migration of PGCs follows complex path by various developing tissues as their disruption impacts on the fertility. Recently, it has been found that dnd is not required for survival of PGCs and dnd-deficient zebrafish PGCs transdifferentiate into the somatic cells. In fish, targeting dnd causes removal of PGCs that ultimately affects sex differentiation. Sterility in various fish species can be achieved by knockdown or knockout of dnd. In our review, we have discussed dnd as a germ cell-specific molecular marker in fish, its interaction with miRNAs, and its use in aquaculture and fish conservation. © 2019, Springer Nature B.V.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10604 - Reproductive biology (medical aspects to be 3)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Fish Physiology and Biochemistry
ISSN
0920-1742
e-ISSN
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Volume of the periodical
47
Issue of the periodical within the volume
neuveden
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
8
Pages from-to
777-784
UT code for WoS article
000665755100013
EID of the result in the Scopus database
2-s2.0-85060550063