Detection of tick-borne encephalits virus RNA in patient samples across different infection stages
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F24%3A00599755" target="_blank" >RIV/60077344:_____/24:00599755 - isvavai.cz</a>
Result on the web
<a href="http://www.ccsss.cz/index.php/ccsss/issue/view/48" target="_blank" >http://www.ccsss.cz/index.php/ccsss/issue/view/48</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Detection of tick-borne encephalits virus RNA in patient samples across different infection stages
Original language description
Tick-borne encephalitis (TBE) is an important neuroviral disease in Europe and Asia, characterised by abiphasic progression: an initial viremic phase with nonspecific symptoms, followed by a neurological phase1. This study evaluated the effectiveness of detecting TBE virus (TBEV) RNA in various clinical samples from 1,125 patients in South Bohemia, Czech Republic, a highly endemic region for TBE. The samples included blood, serum, cerebrospinal fluid (CSF), and urine. The detection of TBEV RNA was most successful in serum during early infection but decreased as the IgG antibody response developed. Rarely, RNA was detectable in serum even after seroconversion.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
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OECD FORD branch
10607 - Virology
Result continuities
Project
<a href="/en/project/LX22NPO5103" target="_blank" >LX22NPO5103: National Institute of Virology and Bacteriology</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů