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Translon: a single term for translated regions

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60077344%3A_____%2F25%3A00643212" target="_blank" >RIV/60077344:_____/25:00643212 - isvavai.cz</a>

  • Alternative codes found

    RIV/61388971:_____/25:00643212 RIV/60076658:12310/25:43910592 RIV/61988987:17310/25:A2603CVT

  • Result on the web

    <a href="https://www.nature.com/articles/s41592-025-02810-3" target="_blank" >https://www.nature.com/articles/s41592-025-02810-3</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1038/s41592-025-02810-3" target="_blank" >10.1038/s41592-025-02810-3</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Translon: a single term for translated regions

  • Original language description

    During translation, ribosomes synthesize polypeptides using RNA molecules as templates. All cellular proteins are products of translation, and the identification of protein-coding regions is the primary goal of genome annotation. Beyond protein synthesis, translation has long been known to have regulatory functions independent of its products1,2. However, only with the advent of ribosome profiling was the broad scale and complexity of translated regions fully appreciated. Recent interest in pervasive translation has exposed a lack of general terminology for translated regions that does not depend on the properties of their products or their sequence. In the absence of such terminology, a range of inconsistently defined terms are used to describe them. These terms are typically variations on ‘open reading frame’ (ORF) — for example, non-canonical ORF (ncORF), RiboSeq ORF, alternative ORF (altORF), translated ORF (tORF), small ORF (smORF), short ORF (sORF) and others. Such terms largely overlap and redundantly describe the same core concept: that the region in question isntranslated.n

  • Czech name

    —

  • Czech description

    —

Classification

  • Type

    J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database

  • CEP classification

    —

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

    —

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2025

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nature Methods

  • ISSN

    1548-7091

  • e-ISSN

    1548-7105

  • Volume of the periodical

    22

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    5

  • Pages from-to

    2002-2006

  • UT code for WoS article

    001637758100001

  • EID of the result in the Scopus database

    2-s2.0-105018346556