Oxime Research

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60162694%3AG44__%2F19%3A00536824" target="_blank" >RIV/60162694:G44__/19:00536824 - isvavai.cz</a>
Result on the web
<a href="https://www.crcpress.com/Chemical-Warfare-Agents-Biomedical-and-Psychological-Effects-Medical-Countermeasures/Lukey-Jr-Salem/p/book/9781498769211" target="_blank" >https://www.crcpress.com/Chemical-Warfare-Agents-Biomedical-and-Psychological-Effects-Medical-Countermeasures/Lukey-Jr-Salem/p/book/9781498769211</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Oxime Research
Original language description
In this chapter, the readers’ attention is turning to antidotal therapy with acetylcholinesterase (AChE) reactivators. Although this group of compounds has been known for more than half a century, there is no single compound that can counteract every nerve agent’s potential to poison. This chapter describes the history of the development of the AChE reactivators, especially within the last 25 years, and their basic pharmacokinetic and pharmacodynamic properties. A special emphasis is given to the structural requirements of these compounds. Finally, new trends in the development of new reactivators are discussed.
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
Chemical Warfare Agents − Biomedical and Psychological Effects, Medical Countermeasures and Emergency Response
ISBN
978-1-4987-6921-1
Number of pages of the result
15
Pages from-to
681-695
Number of pages of the book
826
Publisher name
CRC Press
Place of publication
Boca Raton, USA
UT code for WoS chapter
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