The influence of genistein and genistin on the meiotic maturation of pig oocytes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F05%3A11693" target="_blank" >RIV/60460709:41210/05:11693 - isvavai.cz</a>

Alternative codes found

RIV/60460709:41210/05:###11693

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The influence of genistein and genistin on the meiotic maturation of pig oocytes

Original language description

Phytoestrogens are natural plant substances structurally similar to endogenous estrogens. Genistein is the main phytoestrogen in soya. There are evidences it can affect meiotic maturation of pig oocytes. These effects are attributed to genistein abilityto inhibit tyrozin protein kinase activity. Genistin is an analog of genistein. It has also estrogenic activity but it lack the inhibitory activity for the tyrozin protein kinase. The aim of our study was to verify genistein and genistin effects on meiotic maturation of pig oocytes and to determine, if they are caused by tyrozin protein kinase inhibition or due to an estrogenic activity. Three experiments were performed: 1. Oocytes were cultivated for 24 hours in various concentration of genistein. 2. Oocytes were cultivated for 24 hours in medium with 80 ?g/ml of genistein, then washed and cultivated for another 24 hours in genistein free medium. 3. Oocytes were cultivated for 24 hours in various concentration of genistin. Genistein in

Czech name

Vliv genisteinu a genistinu na meiotické zrání oocytů prasat

Czech description

Phytoestrogens are natural plant substances structurally similar to endogenous estrogens. Genistein is the main phytoestrogen in soya. There are evidences it can affect meiotic maturation of pig oocytes. These effects are attributed to genistein abilityto inhibit tyrozin protein kinase activity. Genistin is an analog of genistein. It has also estrogenic activity but it lack the inhibitory activity for the tyrozin protein kinase. The aim of our study was to verify genistein and genistin effects on meiotic maturation of pig oocytes and to determine, if they are caused by tyrozin protein kinase inhibition or due to an estrogenic activity. Three experiments were performed: 1. Oocytes were cultivated for 24 hours in various concentration of genistein. 2. Oocytes were cultivated for 24 hours in medium with 80 ?g/ml of genistein, then washed and cultivated for another 24 hours in genistein free medium. 3. Oocytes were cultivated for 24 hours in various concentration of genistin. Genistein in

Type

D - Article in proceedings

CEP classification

GG - Zootechnics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Current Problems of Brreding, Health, Growth and Production of Pigs

ISBN

80-85645-50-5

ISSN

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e-ISSN

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Number of pages

4

Pages from-to

257-260

Publisher name

Biologická fakulta

Place of publication

České Budějovice

Event location

České Budějovice

Event date

Feb 9, 2005

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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