The influence of zearalenone on the meiotic maturation of pig oocytes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F05%3A11695" target="_blank" >RIV/60460709:41210/05:11695 - isvavai.cz</a>

Alternative codes found

RIV/60460709:41210/05:###11695

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The influence of zearalenone on the meiotic maturation of pig oocytes

Original language description

Mycoestrogens belong to the group of environmental estrogens. They represent a group of mycotoxins which can act as endogenous estrogens due to their binding ability with estrogen receptors, and thereby affect animals. The aim of our study was to verifyzearalenone effects on meiotic maturation of pig oocytes. Oocytes were cultivated in the M 199 medium under constant conditions of 39 şC and 5 % CO2 in the air for 24 hours to the MI stage. Various amounts of zearalenone (0, 6, 18, 36, 72 ?g/ml) were added to the medium. Zearalenone inhibited maturation of pig oocytes in the stage of germinal vesicle (GV) and late diakinesis (LD) in a dose-dependent manner. The highest effectiveness was observed in the concentration 36 ?g/ml of the medium (GV 52 %, LD 37 %). The zearalenone dose of 72 ?g/ml already had a toxic effect, as many degenerate oocytes were present. The results of our study show that zearalenone can negatively affect maturation of mammalian oocytes and thus disturb fertility of

Czech name

Vliv zearalenonu na meiotické zrání oocytů prasete

Czech description

Mycoestrogens belong to the group of environmental estrogens. They represent a group of mycotoxins which can act as endogenous estrogens due to their binding ability with estrogen receptors, and thereby affect animals. The aim of our study was to verifyzearalenone effects on meiotic maturation of pig oocytes. Oocytes were cultivated in the M 199 medium under constant conditions of 39 şC and 5 % CO2 in the air for 24 hours to the MI stage. Various amounts of zearalenone (0, 6, 18, 36, 72 ?g/ml) were added to the medium. Zearalenone inhibited maturation of pig oocytes in the stage of germinal vesicle (GV) and late diakinesis (LD) in a dose-dependent manner. The highest effectiveness was observed in the concentration 36 ?g/ml of the medium (GV 52 %, LD 37 %). The zearalenone dose of 72 ?g/ml already had a toxic effect, as many degenerate oocytes were present. The results of our study show that zearalenone can negatively affect maturation of mammalian oocytes and thus disturb fertility of

Type

D - Article in proceedings

CEP classification

GG - Zootechnics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

The 4th Symposium of the Society for Biology of Reproduction

ISBN

83-60127-55-7

ISSN

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e-ISSN

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Number of pages

1

Pages from-to

125-125

Publisher name

Deparment of Animal Physiology, University of Agriculture, Krakow

Place of publication

Krakow, Polsko

Event location

Krakow, Polsko

Event date

Sep 22, 2005

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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