The influence of biochanin A on the meiotic maturation of pig oocytes

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F05%3A11694" target="_blank" >RIV/60460709:41210/05:11694 - isvavai.cz</a>

Alternative codes found

RIV/60460709:41210/05:###11694

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The influence of biochanin A on the meiotic maturation of pig oocytes

Original language description

Phytoestrogens are natural plant substances structurally similar to endogenous estrogens. There is evidence, that they influence the maturation of mammalian oocytes. Although biochanin A is one of the first phytoestrogens connected with reproductive disorders, there are no data about its influence on oocytes. The aim of our study was to verify biochanin A effects on the meiotic maturation of pig oocytes. Oocytes were cultivated for 24 hours to the MI stage of meiotic maturation. Various amounts of biochanin A (0, 20, 30, 40, 50, 60, 80 ?g/ml) were added to the medium. Biochanin A inhibited pig oocyte maturation before germinal vesicle breakdown (GVBD) in a dose-dependent manner. The addition of 80 and 60 ?g/ml of biochanin A already acted toxically.

Czech name

Vliv biochaninu A na meiotické zrání oocytů prasete

Czech description

Phytoestrogens are natural plant substances structurally similar to endogenous estrogens. There is evidence, that they influence the maturation of mammalian oocytes. Although biochanin A is one of the first phytoestrogens connected with reproductive disorders, there are no data about its influence on oocytes. The aim of our study was to verify biochanin A effects on the meiotic maturation of pig oocytes. Oocytes were cultivated for 24 hours to the MI stage of meiotic maturation. Various amounts of biochanin A (0, 20, 30, 40, 50, 60, 80 ?g/ml) were added to the medium. Biochanin A inhibited pig oocyte maturation before germinal vesicle breakdown (GVBD) in a dose-dependent manner. The addition of 80 and 60 ?g/ml of biochanin A already acted toxically.

Type

D - Article in proceedings

CEP classification

GG - Zootechnics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2005

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Journal of Applied Biomedicine

ISBN

1214-0287

ISSN

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e-ISSN

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Number of pages

2

Pages from-to

29-30

Publisher name

Biologická fakulta

Place of publication

České Budějovice

Event location

České Budějovice

Event date

Oct 24, 2005

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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