Prooxidative effect of bisphenol S on porcine oocytes meiotic maturation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60460709%3A41210%2F18%3A78340" target="_blank" >RIV/60460709:41210/18:78340 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Prooxidative effect of bisphenol S on porcine oocytes meiotic maturation
Original language description
Many substances introduced to the environment exert endocrine disrupting effects and negatively affect human and animal reproduction. Plasticizers bisphenols belongs to a group of the most studied endocrine disruptors. However, the effects of bisphenol S on reproduction is not well characterized. It is known that some endocrine disruptors can induce in cells oxidative stress. The aim of our study was to test the hypothesis that BPS induces oxidative stress through ROS production in porcine oocytes during their meiotic maturation. Maturing oocytes were cultured in the presence of 300 nM and 30 uM of BPS, and levels of ROS in oocytes after 24 and 48 hours of cultivation were evaluated. Both concentration of BPS statistically significantly increased ROS production after cultivation. The experiments confirmed that BPS influences ROS production and induces oxidative stress during porcine oocytes meiotic maturation
Czech name
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Czech description
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Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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