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Antifungal Polyamides of Hydroxycinnamic Acids from Sunflower Bee Pollen

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22310%2F18%3A43916666" target="_blank" >RIV/60461373:22310/18:43916666 - isvavai.cz</a>

  • Alternative codes found

    RIV/60461373:22330/18:43916666 RIV/60461373:22340/18:43916666 RIV/60461373:22810/18:43916666

  • Result on the web

    <a href="http://dx.doi.org/10.1021/acs.jafc.8b03976" target="_blank" >http://dx.doi.org/10.1021/acs.jafc.8b03976</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1021/acs.jafc.8b03976" target="_blank" >10.1021/acs.jafc.8b03976</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Antifungal Polyamides of Hydroxycinnamic Acids from Sunflower Bee Pollen

  • Original language description

    The aim of the bioassay-guided fractionation was the selection of the most potent group of compounds responsible for the protection of sunflower bee pollen grains. Synthesis of prospective antifungal polyamides of hydroxycinnamic acids was based on previous structural elucidation of ethanol soluble fraction by H-1,H-1-PFG-COSY, H-1,C-13-HSQC, FT-IR, FT-Raman, and LC-MS experiments. The main compounds found were tri-p-coumaroylspermidines accompanied by other HCAA of spermidine and putrescine. Several model HCAA derivatives were prepared to test their antifungal activity against widespread spoilage fungi (A. niger 42 CCM 8189, F. culmorum DMF 0103, and P. verrucosum DMF 0023). A. niger CCM 8189 and F. culmorum DMF 0103 exhibited higher resistance to the antifungal effects of hydroxycinnamic acid amides, whereas P. verrucosum DMF 0023 was the most sensitive strain. It has been discovered the effect of HCAA polarity on the role of secondary metabolites in the microbial protection of pollen grains. The combination of bioassay-guided fractionation, structural elucidation, selection of prospective compounds, and their synthesis to determine their antifungal properties could be considered as an original approach.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    21101 - Food and beverages

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of Agricultural and Food Chemistry

  • ISSN

    0021-8561

  • e-ISSN

  • Volume of the periodical

    66

  • Issue of the periodical within the volume

    42

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    9

  • Pages from-to

    11018-11026

  • UT code for WoS article

    000448754600009

  • EID of the result in the Scopus database

    2-s2.0-85055093412