Ferrocenylethynyl derivatives of nucleoside triphosphates: Synthesis, incorporation, electrochemistry, and bioanalytical applications

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F07%3A00093065" target="_blank" >RIV/61388963:_____/07:00093065 - isvavai.cz</a>

Alternative codes found

RIV/68081707:_____/07:00093065

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Ferrocenylethynyl derivatives of nucleoside triphosphates: Synthesis, incorporation, electrochemistry, and bioanalytical applications

Original language description

Modified dNTP bearing ferrocene labels linked via a conjugate acetylene spacer were prepared by single-step aqueous-phase cross-coupling reactions. The Fc-labeled dNTPs were good substrates for DNA polymerases and were efficiently incorporated to DNA byprimer extension. Prospective bioanalytical applications are outlined.

Czech name

Ferocénethynylové deriváty nukleosid trifosfátů. Syntéza, inkorporace, elektrochemie a bioanalytické aplikace

Czech description

Nukleotid trifosfáty nesoucí ferocén připojené pomocí ethylénového linkeru byly syntetizovány pomocí jednokrokové cross-coupling reakce ve vodném prostředí. Tyto nukleotid trifosfáty byly inkorporovány do molekul oligonukleotidů pomocí DNA polymeráz. Takto připravené značené oligonukleotidy byly použity v bioanalytických aplikacích.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2007

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemistry - A European Journal

ISSN

0947-6539

e-ISSN

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Volume of the periodical

139

Issue of the periodical within the volume

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Country of publishing house

DE - GERMANY

Number of pages

7

Pages from-to

9527-9533

UT code for WoS article

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EID of the result in the Scopus database

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