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Cell-penetrating peptides in the intracellular delivery of viral nanoparticles

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F21%3A00545044" target="_blank" >RIV/61388963:_____/21:00545044 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11310/21:10431295

  • Result on the web

    <a href="https://doi.org/10.1016/bs.vh.2021.06.010" target="_blank" >https://doi.org/10.1016/bs.vh.2021.06.010</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/bs.vh.2021.06.010" target="_blank" >10.1016/bs.vh.2021.06.010</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cell-penetrating peptides in the intracellular delivery of viral nanoparticles

  • Original language description

    Cell-penetrating peptides (CPPs) are a promising tool for the intracellular delivery of cargo. Due to their ability to cross membranes while also cotransporting various cargoes, they offer great potential for biomedical applications. Several CPPs have been derived from viral proteins with natural roles in the viral replication cycle that require them to breach or fuse to cellular membranes. Additionally, the ability of viruses to cross membranes makes viruses and virus-based particles a convenient model for research on nanoparticle delivery and nanoparticle-mediated gene therapy. In this chapter, we aim to characterize CPPs derived from both structural and nonstructural viral proteins. Their function as enhancers of viral infection and transduction by viral nanoparticles as well as the main features of viral CPPs employed in intracellular cargo delivery are summarized to emphasize their potential use in nanomedicine.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    10608 - Biochemistry and molecular biology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2021

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Hormones, regulators and viruses

  • ISBN

    978-0-323-90731-6

  • Number of pages of the result

    30

  • Pages from-to

    47-76

  • Number of pages of the book

    332

  • Publisher name

    Academic Press

  • Place of publication

    Cambridge

  • UT code for WoS chapter

    000750920700004