Impact of Dietary Gluten on Regulatory T Cells and Th17 Cells in BALB/c Mice

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F12%3A00382232" target="_blank" >RIV/61388971:_____/12:00382232 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pone.0033315" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0033315</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0033315" target="_blank" >10.1371/journal.pone.0033315</a>

Result language
angličtina
Original language name
Impact of Dietary Gluten on Regulatory T Cells and Th17 Cells in BALB/c Mice
Original language description
Dietary gluten influences the development of type 1 diabetes (T1D) and a gluten-free (GF) diet has a protective effect on the development of T1D. Gluten may influence T1D due to its direct effect on intestinal immunity; however, these mechanisms have notbeen adequately studied. We studied the effect of a GF diet compared to a gluten-containing standard (STD) diet on selected T cell subsets, associated with regulatory functions as well as proinflammatory Th17 cells, in BALB/c mice. Furthermore, we assessed diet-induced changes in the expression of various T cell markers, and determined if changes were confined to intestinal or non-intestinal lymphoid compartments
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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