Divergent branches of mitochondrial signaling regulate specific genes and the viability of specialized cell types of differentiated yeast colonies
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388971%3A_____%2F16%3A00463618" target="_blank" >RIV/61388971:_____/16:00463618 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/16:10324147
Result on the web
<a href="http://dx.doi.org/10.18632/oncotarget.8084" target="_blank" >http://dx.doi.org/10.18632/oncotarget.8084</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.18632/oncotarget.8084" target="_blank" >10.18632/oncotarget.8084</a>
Alternative languages
Result language
angličtina
Original language name
Divergent branches of mitochondrial signaling regulate specific genes and the viability of specialized cell types of differentiated yeast colonies
Original language description
Mitochondrial retrograde signaling mediates communication from altered mitochondria to the nucleus and is involved in many normal and pathophysiological changes, including cell metabolic reprogramming linked to cancer development and progression in mammals. The major mitochondrial retrograde pathway described in yeast includes three activators, Rtg1p, Rtg2p and Rtg3p, and repressors, Mks1p and Bmh1p/Bmh2p. Using differentiated yeast colonies, we show that Mks1p-Rtg pathway regulation is complex and includes three branches that divergently regulate the properties and fate of three specifically localized cell subpopulations via signals from differently altered mitochondria.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
OncoTarget
ISSN
1949-2553
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
13
Country of publishing house
US - UNITED STATES
Number of pages
16
Pages from-to
15299-15314
UT code for WoS article
000375692900004
EID of the result in the Scopus database
2-s2.0-84971655111