Methods for attachment of antibodies onto optical biosensors

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F06%3A00039859" target="_blank" >RIV/61389013:_____/06:00039859 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Methods for attachment of antibodies onto optical biosensors

Original language description

Biosensors based on the evanescent light wave can detect in real-time the binding of analytes to specific bioreceptors immobilised on the surface of an optical transducer. Various methods for antibody attachment to gold surface of SPR sensors or metal and silicone oxide surfaces of waveguide based sensors are discussed in relation to the number of immobilized antibodies, preservation of the antigen binding site activity, accessibility of the binding sites for the analytes, and sensor resistance againstthe adsorption of nonspecific compounds from tested biological media. Possible immunosensor applications are compared with the contemporary immunosorbent assays.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

CD - Macromolecular chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2006

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Optical Chemical Sensors

ISBN

1-4020-4609-X

ISSN

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e-ISSN

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Number of pages

15

Pages from-to

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Publisher name

Springer

Place of publication

Dordrecht

Event location

Erice

Event date

Jul 29, 2004

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

000237479000018