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Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F08%3A00306669" target="_blank" >RIV/61389013:_____/08:00306669 - isvavai.cz</a>

  • Alternative codes found

    RIV/61389005:_____/08:00306669

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Thermoresponsive polymer for local radiotherapy with doxorubicin bound via a newly developed hydrolytically labile bond

  • Original language description

    A new polymeric drug delivery system designed for possible local chemoradiotherapy using injectable thermoresponsive polymer with radionuclide and doxorubicin, which serves as an antiproliferative agent and hydrophobic moiety controlling bioerosion in the same time, was synthesized and characterized. Doxorubicin is bound to the polymer carrier by a newly developed N-glycosylamine bond.

  • Czech name

    Termoresponsivní polymery pro lokální radioterapii s doxorubicinem vázaným nově vyvinutou hydrolyticky labilní vazbou

  • Czech description

    Byl připraven a charakterizován nový injikovatelný polymerní systém pro lokální chemoradioterapii s vázaným radionuklidem a doxorubicinem jako skupinou, která kromě svého protinádorového působení funguje jako hydrofóbní jednotka řídící biodegradaci. Doxorubicin byl na polymer navázán nově vyvinutou N-glykosylaminovou vazbou.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    CD - Macromolecular chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Abstract Book - Tenth European Symposium on Controlled Drug Delivery

  • ISBN

    978-90-365-2653-1

  • ISSN

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

    174-177

  • Publisher name

    University of Twente

  • Place of publication

    Noordwijk aan Zee

  • Event location

    Noordwijk aan Zee

  • Event date

    Apr 2, 2008

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article