Silica-coated .gamma.-Fe2O3 nanoparticles: preparation and engulfment by mammalian macrophages

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389013%3A_____%2F13%3A00394385" target="_blank" >RIV/61389013:_____/13:00394385 - isvavai.cz</a>

Alternative codes found

RIV/67985530:_____/13:00394385

Result on the web

<a href="http://dx.doi.org/10.1166/jnd.2013.1020" target="_blank" >http://dx.doi.org/10.1166/jnd.2013.1020</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1166/jnd.2013.1020" target="_blank" >10.1166/jnd.2013.1020</a>

Result language

angličtina

Original language name

Silica-coated .gamma.-Fe2O3 nanoparticles: preparation and engulfment by mammalian macrophages

Original language description

Maghemite (?-Fe2O3) nanoparticles were prepared by coprecipitation of Fe(II) and Fe(III) salts followed by oxidation of Fe3O4 with sodium hypochlorite. The ?-Fe2O3 nanoparticles were then coated by a silica shell using tetramethyl orthosilicate producing?-Fe2O3@SiO2 particles. In order to introduce amino groups, the surface of the ?-Fe2O3@SiO2 particles was coated with a second silica shell using (3-aminopropyl)triethoxysilane, resulting in ?-Fe2O3@SiO2-NH2 nanoparticles. The particles were characterized by scanning and transmission electron microscopy (SEM and TEM), dynamic light scattering (DLS) and Fourier-transform infrared (FT-IR) spectroscopy in terms of determination of morphology, particle size, polydispersity and presence of functional groups. Atomic absorption spectroscopy (AAS) was used for determination of the iron content. Moreover, induced magnetization and temperature-dependent magnetic susceptibility were investigated. In the biological experiments, ?-Fe2O3@SiO2 and ?-

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CD - Macromolecular chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Nanopharmaceutics and Drug Delivery

ISSN

2167-9312

e-ISSN

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Volume of the periodical

1

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

11

Pages from-to

182-192

UT code for WoS article

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EID of the result in the Scopus database

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