Fabrication and characterization of hydroxyapatite-strontium/polylactic acid composite for potential applications in bone regeneration
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61389021%3A_____%2F23%3A00584070" target="_blank" >RIV/61389021:_____/23:00584070 - isvavai.cz</a>
Result on the web
<a href="https://link.springer.com/article/10.1007/s00289-022-04541-3" target="_blank" >https://link.springer.com/article/10.1007/s00289-022-04541-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00289-022-04541-3" target="_blank" >10.1007/s00289-022-04541-3</a>
Alternative languages
Result language
angličtina
Original language name
Fabrication and characterization of hydroxyapatite-strontium/polylactic acid composite for potential applications in bone regeneration
Original language description
In this study, polylactic acid (PLA) was reinforced with hydroxyapatite (HAp) microparticles and strontium (Sr) powder via the melt extrusion/hot pressing manufacturing process to produce scaffolding materials with bone regeneration potentials. After the fabrication of the materials, the physico-chemical and mechanical characteristics were investigated. The morphology of the precursors for scaffold fabrication and the resulting composites was investigated. The structural characterization showed the semicrystalline nature of the PLA polymer and the characteristic reflections of HAp loading in the polymer matrix. The functional groups of the PLA matrix and the loaded variants showed the characteristic bands of HAp and Sr for the PLA-HAp and PLA-HAp-Sr scaffolding materials, respectively. Moreover, the physical property evaluation showed that with the addition of HAp, the porosity of the PLA-HAp scaffolds was reduced. However, the addition of Sr increased the porosity of the scaffolds, and this can possibly be ascribed to the grain refinement ability of strontium. The mechanical measurement data showed that the inclusion of Sr produced the maximum average Vickers hardness value of 49.1 HV. The composite scaffolds showed bioactivity potentials, thus, they can serve as suitable bone regeneration materials.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20505 - Composites (including laminates, reinforced plastics, cermets, combined natural and synthetic fibre fabrics; filled composites)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Polymer Bulletin
ISSN
0170-0839
e-ISSN
1436-2449
Volume of the periodical
80
Issue of the periodical within the volume
10
Country of publishing house
DE - GERMANY
Number of pages
18
Pages from-to
10997-11014
UT code for WoS article
001153420100006
EID of the result in the Scopus database
2-s2.0-85142711428