Toxicity and mutagenicity of low-metallic automotive brake pad materials

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989100%3A27640%2F16%3A86099758" target="_blank" >RIV/61989100:27640/16:86099758 - isvavai.cz</a>

Alternative codes found

RIV/61988987:17310/16:A1701JHE

Result on the web

<a href="http://dx.doi.org/10.1016/j.ecoenv.2016.05.003" target="_blank" >http://dx.doi.org/10.1016/j.ecoenv.2016.05.003</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ecoenv.2016.05.003" target="_blank" >10.1016/j.ecoenv.2016.05.003</a>

Result language

angličtina

Original language name

Toxicity and mutagenicity of low-metallic automotive brake pad materials

Original language description

Organic friction materials are standardly used in brakes of small planes, railroad vehicles, trucks and passenger cars. The growing transportation sector requires a better understanding of the negative impact related to the release of potentially hazardous materials into the environment. This includes brakes which can release enormous quantities of wear particulates. This paper addresses in vitro detection of toxic and mutagenic potency of one model and two commercially available low-metallic automotive brake pads used in passenger cars sold in the EU market. The model pad made in the laboratory was also subjected to a standardized brake dynamometer test and the generated non-airborne wear particles were also investigated. Qualitative "organic composition" was determined by GC/MS screening of dichloromethane extracts. Acute toxicity and mutagenicity of four investigated sample types were assessed in vitro by bioluminescence assay using marine bacteria Vibrio fischeri and by two bacterial bioassays i) Ames test on Salmonella typhimurium His(-)and ii) SOS Chromotest using Escherichia coli PQ37 strain. Screening of organic composition revealed a high variety of organic compounds present in the initial brake pads and also in the generated non-airborne wear debris. Several detected compounds are classified by IARC as possibly carcinogenic to humans, e.g. benzene derivatives. Acute toxicity bioassay revealed a response of bacterial cells after exposure to all samples used. Phenolic resin and wear debris were found to be acutely toxic; however in term of mutagenicity the response was negative. All non friction exposed brake pad samples (a model pad and two commercial pad samples) were mutagenic with metabolic activation in vitro

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

DN - Environmental impact on health

OECD FORD branch

—

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Ecotoxicology and environmental safety

ISSN

0147-6513

e-ISSN

—

Volume of the periodical

131

Issue of the periodical within the volume

SEP 2016

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

37-44

UT code for WoS article

000378020800006

EID of the result in the Scopus database

2-s2.0-84966263799