Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15110%2F08%3A33115986" target="_blank" >RIV/61989592:15110/08:33115986 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Association of chronic stable angina pectoris with MCP-1-2518 A/G single nucleotide polymorphism in the Slovak population
Original language description
Polymorphic gene variants in chemokine MCP-1 (CCL2) gene were determined by PCR-SSP in 151 patients with chronic angina pectoris (AP) and in 449 healthy subjects, both of Slovak ethnicity. The frequency of MCP-1-2518 GG homozygous individuals was increased in patients compared to control subjects (p=0.003); the increase was more pronounced in males and it was present both in early and late AP. The reported observation implicates the tested polymorphic MCP-1 gene variant in chronic AP, at least in patients of Slovak ethnicity.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EC - Immunology
OECD FORD branch
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Project
<a href="/en/project/ME%20856" target="_blank" >ME 856: Polymorphism in genes for chemotactic cytokines and their receptors in Slavonic patients with myocardial infarction</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2008
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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