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HRP-like activity og bare and modified magnetic nanoparticles

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33156631" target="_blank" >RIV/61989592:15310/15:33156631 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    HRP-like activity og bare and modified magnetic nanoparticles

  • Original language description

    The horseradish peroxidase conjugated with antibody is used in many biochemical applications such as immunoassays or Western blots primarily for its ability to amplify a weak signal and increase detectability of a target molecules. Horseradish peroxidaseis susceptible to damage due to high/low temperatures, or by changing the pH. The magnetic particles exhibit the same behavior as horseradish peroxidase, and if a suitable substrate is used, this reaction could be detectable by spectrophotometer too. They catalyze the reaction in a broader range of temperature and pH compared to peroxidase. The catalytic reaction of magnetic nanoparticles is hydrogen peroxide dependent. Magnetic particles exhibit stronger peroxidase-like activity, but for practical applications it is necessary to modify the surface to ensure the specificity of binding to the target structure and also improve biocompatibility and stability. Magnetic nanoparticles modified with chitosan were compared with particles witho

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    BM - Solid-state physics and magnetism

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    6th International Conference NANOCON 2014

  • ISBN

    978-80-87294-53-6

  • ISSN

  • e-ISSN

  • Number of pages

    6

  • Pages from-to

    588-593

  • Publisher name

    Tanger

  • Place of publication

    Ostrava

  • Event location

    Brno

  • Event date

    Nov 5, 2014

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article

    000350636300101