HRP-like Activity of Bare and Modified Magnetic Nanoparticles
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61989592%3A15310%2F15%3A33156636" target="_blank" >RIV/61989592:15310/15:33156636 - isvavai.cz</a>
Result on the web
<a href="http://konsys-t.tanger.cz/files/proceedings/20/reports/3269.pdf" target="_blank" >http://konsys-t.tanger.cz/files/proceedings/20/reports/3269.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
HRP-like Activity of Bare and Modified Magnetic Nanoparticles
Original language description
The horseradish peroxidase conjugated with antibody is used in many biochemical applications such as immunoassays or Western blots primarily for its ability to amplify a weak signal and increase detectability of a target molecules. Horseradish peroxidaseis susceptible to damage due to high/low temperatures, or by changing the pH. The magnetic particles exhibit the same behavior as horseradish peroxidase, and if a suitable substrate is used, this reaction could be detectable by spectrophotometer too. They catalyze the reaction in a broader range of temperature and pH compared to peroxidase. The catalytic reaction of magnetic nanoparticles is hydrogen peroxide dependent. Magnetic particles exhibit stronger peroxidase-like activity, but for practical applications it is necessary to modify the surface to ensure the specificity of binding to the target structure and also improve biocompatibility and stability. Magnetic nanoparticles modified with chitosan were compared with particles witho
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CF - Physical chemistry and theoretical chemistry
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Conference Proceedings of 6th International Conference NANOCON 2014
ISBN
978-80-87294-53-6
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
588-593
Publisher name
Tanger
Place of publication
Ostrava
Event location
Brno
Event date
Nov 5, 2014
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
000350636300101