Occurrence of cell death in cancer cell line PC-3 after treatment of plumbagin
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F14%3A43908767" target="_blank" >RIV/62156489:43210/14:43908767 - isvavai.cz</a>
Result on the web
<a href="https://mnet.mendelu.cz/mendelnet2014/mnet_2014_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2014/mnet_2014_full.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Occurrence of cell death in cancer cell line PC-3 after treatment of plumbagin
Original language description
The aim of this study, which is focused on occurrence of cell death in cancer cell line PC-3 after treatment of plumbagin is get information about distribution of normal, apoptotic and autophagic cells by exposure to plumbagin. Plumbagin is one of the simplest plant secondary metabolite of three major phylogenic families - Plumbaginaceae, Droseraceae and Ebenceae. Plumbagin assigns highly potent biological activities, for example antioxidant, antiinflammatory, anticancer, antibacterial and antifungal activities. Cancer cell line PC-3 is derived from the 4st degree of adenocarcinoma of prostate. The type of cell death is important for developing of new diagnostical approaches. In this study types of cell death were studied by using experiment which take48 hours. During this time cells were exposed to plumbagin, which cause one of type of cell death. Action of this metabolite was finished after certain hour depending on the number of sample and after that samples were analysed by light
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
EA - Morphology and cytology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
MendelNet 2014: Proceedings of International Ph.D. Students Conference
ISBN
978-80-7509-174-1
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
494-498
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Nov 19, 2014
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000362518300094