Antimicrobial activity of PLGA nanoparticles

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F20%3A43919601" target="_blank" >RIV/62156489:43210/20:43919601 - isvavai.cz</a>
Result on the web
<a href="https://mnet.mendelu.cz/mendelnet2020/mnet_2020_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2020/mnet_2020_full.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Antimicrobial activity of PLGA nanoparticles
Original language description
Nowadays, one of the major problems in the world is occurring antimicrobial resistance of bacteria. Nanoencapsulation offers great potential in overcoming of antibiotics resistance using natural compounds for delivery. PLGA nanoparticles with entrapped mupirocin and fish oil have promising potential for nanodelivery system. Mupirocin is effective in inhibition of major grampositive bacteria. Fish oil has anti-inflammatory and regenerating effects in the healing process of the skin due to the content of long-chain n-3 polyunsaturated fatty acids (PUFAs). Expectedly, no antimicrobial effect was observed by PLGA with encapsulated fish oil unlike PLGA with encapsulated mupirocin. Unfortunately, the antimicrobial activity of mupirocin alone was significant compared to encapsulated mupirocin. Despite the following results, PLGA nanoparticles should be further studied and their production improved for other purposes.
Czech name
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Czech description
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Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
MendelNet 2020: Proceedings of International PhD Students Conference
ISBN
978-80-7509-765-1
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
517-521
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Nov 11, 2020
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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