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Single nucleotide polymorphisms in four functionally related immune response genes in the horse: CD14, TLR4, Cepsilon and FcR1 alpha.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F05%3A43871744" target="_blank" >RIV/62157124:16170/05:43871744 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1111/j.1744-313X.2005.00522.x" target="_blank" >http://dx.doi.org/10.1111/j.1744-313X.2005.00522.x</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/j.1744-313X.2005.00522.x" target="_blank" >10.1111/j.1744-313X.2005.00522.x</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Single nucleotide polymorphisms in four functionally related immune response genes in the horse: CD14, TLR4, Cepsilon and FcR1 alpha.

  • Original language description

    The objective of this study was to identify single nucleotide polymorphisms (SNPs) within four functionally related immune response genes in the horse, and to develop genotyping techniques that could be useful for future genomic studies of horse infectious and allergic diseases. The genes analysed were: the lipopolysaccharide (LPS) receptor gene CD14, the toll-like receptor 4 gene TLR4, the gene Cepsilon encoding the IgE heavy chain molecule and the gene FcepsilonR1 alpha coding for the alpha subunit ofthe IgE receptor molecule. The methods developed for genotyping and haplotyping the SNPs identified represent, along with markers described previously, a potentially useful tool for genomic analysis of the function and role of these genes in immunity and in mechanisms of disease.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GP523%2F03%2FP089" target="_blank" >GP523/03/P089: Identification and mapping of genes as a ground of function genomic analysis of innate immunity response in the horses</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Immunogenetics

  • ISSN

    1744-3121

  • e-ISSN

  • Volume of the periodical

    32

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    7

  • Pages from-to

    277-283

  • UT code for WoS article

    000231902900003

  • EID of the result in the Scopus database