Natural Killer Cell Receptor Genes in the Family Equidae: Not only Ly49
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62157124%3A16170%2F13%3A43872346" target="_blank" >RIV/62157124:16170/13:43872346 - isvavai.cz</a>
Alternative codes found
RIV/62157124:16810/13:43872346
Result on the web
<a href="http://dx.doi.org/10.1371/journal.pone.0064736" target="_blank" >http://dx.doi.org/10.1371/journal.pone.0064736</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1371/journal.pone.0064736" target="_blank" >10.1371/journal.pone.0064736</a>
Alternative languages
Result language
angličtina
Original language name
Natural Killer Cell Receptor Genes in the Family Equidae: Not only Ly49
Original language description
Natural killer (NK) cells have important functions in immunity. NK recognition in mammals can be mediated through killer cell immunoglobulin-like receptors (KIR) and/or killer cell lectin-like Ly49 receptors. Genes encoding highly variable NK cell receptors (NKR) represent rapidly evolving genomic regions. Single-copy low polymorphic NKR genes present in one mammalian species may expand into highly polymorphic multigene families in other species. In contrast to other non-rodent mammals, multiple Ly49-like genes appear to exist in the horse, while no functional KIR genes were observed in this species. In this study, Ly49 and KIR were sought and their evolution was characterized in the entire family Equidae. Genomic sequences retrieved showed the presence of at least five highly conserved polymorphic Ly49 genes in horses, asses and zebras. These findings confirmed that the expansion of Ly49 occurred in the entire family. Several KIR-like sequences were also identified in the genome of Eq
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
PLoS ONE
ISSN
1932-6203
e-ISSN
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Volume of the periodical
8
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
2
Pages from-to
"neuvedeno"
UT code for WoS article
000319733000089
EID of the result in the Scopus database
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