Behavioral toxicity of nerve agents
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F15%3A50004532" target="_blank" >RIV/62690094:18470/15:50004532 - isvavai.cz</a>
Alternative codes found
RIV/00179906:_____/15:10320688
Result on the web
<a href="http://dx.doi.org/10.1016/B978-0-12-800159-2.00035-X" target="_blank" >http://dx.doi.org/10.1016/B978-0-12-800159-2.00035-X</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/B978-0-12-800159-2.00035-X" target="_blank" >10.1016/B978-0-12-800159-2.00035-X</a>
Alternative languages
Result language
angličtina
Original language name
Behavioral toxicity of nerve agents
Original language description
The behavioral changes belong to the most important and frequent symptoms of acute and delayed toxicity of organophosphorus (OP) nerve agents. The incidence of behavioral effects is higher in individuals who have been severely exposed to nerve agents, but they may occur in individuals who have received low-level exposure below those producing convulsions and other severe clinical signs of toxicity. The behavioral effects usually start within a few hours and last from several days to several weeks or months. The most frequent symptoms include disruption of cognitive functions, feelings of uneasiness, tenseness, and fatigue. Persistent severe alteration in behavior and cognitive functions, especially impairment of learning and memory, was observed afterthe exposure to high doses of nerve agents as a result of severe brain neuropathology that involves neuronal degeneration and necrosis of various brain regions, including the hippocampus that is connected with the alteration of cognitive
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
KA - Militarism
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Handbook of toxicology of chemical warfare agents
ISBN
978-0-12-800159-2
Number of pages of the result
11
Pages from-to
477-487
Number of pages of the book
1184
Publisher name
Elsevier
Place of publication
Amsterdam
UT code for WoS chapter
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