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Behavioral toxicity of nerve agents

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62690094%3A18470%2F15%3A50004532" target="_blank" >RIV/62690094:18470/15:50004532 - isvavai.cz</a>

  • Alternative codes found

    RIV/00179906:_____/15:10320688

  • Result on the web

    <a href="http://dx.doi.org/10.1016/B978-0-12-800159-2.00035-X" target="_blank" >http://dx.doi.org/10.1016/B978-0-12-800159-2.00035-X</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/B978-0-12-800159-2.00035-X" target="_blank" >10.1016/B978-0-12-800159-2.00035-X</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Behavioral toxicity of nerve agents

  • Original language description

    The behavioral changes belong to the most important and frequent symptoms of acute and delayed toxicity of organophosphorus (OP) nerve agents. The incidence of behavioral effects is higher in individuals who have been severely exposed to nerve agents, but they may occur in individuals who have received low-level exposure below those producing convulsions and other severe clinical signs of toxicity. The behavioral effects usually start within a few hours and last from several days to several weeks or months. The most frequent symptoms include disruption of cognitive functions, feelings of uneasiness, tenseness, and fatigue. Persistent severe alteration in behavior and cognitive functions, especially impairment of learning and memory, was observed afterthe exposure to high doses of nerve agents as a result of severe brain neuropathology that involves neuronal degeneration and necrosis of various brain regions, including the hippocampus that is connected with the alteration of cognitive

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

    KA - Militarism

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Handbook of toxicology of chemical warfare agents

  • ISBN

    978-0-12-800159-2

  • Number of pages of the result

    11

  • Pages from-to

    477-487

  • Number of pages of the book

    1184

  • Publisher name

    Elsevier

  • Place of publication

    Amsterdam

  • UT code for WoS chapter