Which component of treatment is important for changes of cortical epileptic afterdischarges after status epilepticus in immature rats?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F17%3A00475001" target="_blank" >RIV/67985823:_____/17:00475001 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.neulet.2017.02.043" target="_blank" >http://dx.doi.org/10.1016/j.neulet.2017.02.043</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.neulet.2017.02.043" target="_blank" >10.1016/j.neulet.2017.02.043</a>
Alternative languages
Result language
angličtina
Original language name
Which component of treatment is important for changes of cortical epileptic afterdischarges after status epilepticus in immature rats?
Original language description
Role of lithium chloride and paraldehyde in acute changes after lithium-pilocarpine status epilepticus (SE) induced at postnatal day 12 was studied in 15-day-old rats. In addition to SE group four other groups were formed: naive animals without any injection, lithium chloride group, paraldehyde group and lithium-paraldehyde group. Cortical epileptic afterdischarges (CxADs) induced by increasing intensities of stimulation current were used as a measure of excitability. SE animals did not exhibit any change in duration of CxADs with increasing stimulation intensity in contrast to na ve control with a progressive prolongation of CxAD. LiCI group was similar to SE rats whereas paraldehyde and lithium-paraldehyde groups exhibited some progress in duration of ADs. Lithium chloride participates in short-term changes of CxADs after SE. Paraldehyde and combination of lithium paraldehyde are similar to na ve controls.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Neuroscience Letters
ISSN
0304-3940
e-ISSN
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Volume of the periodical
644
Issue of the periodical within the volume
Mar 22
Country of publishing house
IE - IRELAND
Number of pages
4
Pages from-to
1-4
UT code for WoS article
000407529300001
EID of the result in the Scopus database
2-s2.0-85013790767