Minoxidil decreases collagen I deposition and tissue-like contraction in clubfoot-derived cells: a way to improve conservative treatment of relapsed clubfoot?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985823%3A_____%2F21%3A00547576" target="_blank" >RIV/67985823:_____/21:00547576 - isvavai.cz</a>
Alternative codes found
RIV/00064211:_____/20:W0000010 RIV/00216208:11510/21:10415820 RIV/00216208:11110/21:10415820 RIV/00216208:11130/21:10415820 RIV/00064211:_____/21:W0000052
Result on the web
<a href="https://doi.org/10.1080/03008207.2020.1816992" target="_blank" >https://doi.org/10.1080/03008207.2020.1816992</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/03008207.2020.1816992" target="_blank" >10.1080/03008207.2020.1816992</a>
Alternative languages
Result language
angličtina
Original language name
Minoxidil decreases collagen I deposition and tissue-like contraction in clubfoot-derived cells: a way to improve conservative treatment of relapsed clubfoot?
Original language description
Clubfoot is a congenital deformity affecting the musculoskeletal system, resulting in contracted and stiff tissue in the medial part of the foot. Minoxidil (MXD) has an inhibitory effect on lysyl hydroxylase, which influences the quality of extracellular matrix crosslinking, and could therefore be used to reduce the stiffness and to improve the flexibility of the tissue. We assessed the in vitro antifibrotic effects of minoxidil on clubfoot-derived cells.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30211 - Orthopaedics
Result continuities
Project
<a href="/en/project/NV17-31564A" target="_blank" >NV17-31564A: Improvement of non-invasive fibrosis treatment of congenital pes equinovarus.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Connective Tissue Research
ISSN
0300-8207
e-ISSN
1607-8438
Volume of the periodical
62
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
16
Pages from-to
554-569
UT code for WoS article
000571321300001
EID of the result in the Scopus database
2-s2.0-85091144762