An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F19%3A00511793" target="_blank" >RIV/68081707:_____/19:00511793 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15310/19:73597253
Result on the web
<a href="https://www.nature.com/articles/s41598-019-49774-x.pdf" target="_blank" >https://www.nature.com/articles/s41598-019-49774-x.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41598-019-49774-x" target="_blank" >10.1038/s41598-019-49774-x</a>

Result language
angličtina
Original language name
An anticancer Os(II) bathophenanthroline complex as a human breast cancer stem cell-selective, mammosphere potent agent that kills cells by necroptosis
Original language description
Here, we show that Os(II) complex [Os(eta(6)-pcym)(bphen)(dca)]PF6 (pcym =p-cymene, bphen = bathophenanthroline, and dca = dichloroacetate), is capable of efficient and selective killing CSCs in heterogeneous populations of human breast cancer cells MCF-7 and SKBR-3.
Czech name
—
Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10601 - Cell biology

Project
<a href="/en/project/GA17-05302S" target="_blank" >GA17-05302S: Targeting cancer stem cells by antitumor metallodrugs. Studies on mechanism of action</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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