An additional marker of ventricular dyssynchrony

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F15%3A00456399" target="_blank" >RIV/68081731:_____/15:00456399 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
An additional marker of ventricular dyssynchrony
Original language description
Patients suffering from heart failure with left bundle branch block (LBBB) can be effectively treated by resynchronization therapy (CRT). The ejection fraction, QRS duration (QRSd) and QRS morphology are the main selection criteria. Unfortunately, approximately one-third of CRT recipients are non-responders. Here we introduce an additional marker capable of distinguishing ventricular dyssynchrony more accurately. Methods: Ultra-high-frequency (UHF, sampling 25 kHz) 12-lead ECG, resting supine position,was measured. We analyzed 21 LBBB patients selected for CRT; the QRSd min/mean/max was 130/163/190 ms. Amplitude envelopes in the 500?1,000 Hz passband were computed and averaged with an R-wave trigger for each patient in the V1 and V6 leads. V1-V6 dyssynchrony (DYS) was computed as the time difference between UHF amplitude maximums in the V1 and V6 QRS complex region. The DYS parameter min/mean/max was 1/68/115 ms. Patients with a small value of the DYS parameter, in spite of the fact t
Czech name
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Czech description
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Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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