Biventricular pacing optimization by means of the dyssynchrony parameter
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F16%3A00474791" target="_blank" >RIV/68081731:_____/16:00474791 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.22489/CinC.2016.051-263" target="_blank" >http://dx.doi.org/10.22489/CinC.2016.051-263</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.22489/CinC.2016.051-263" target="_blank" >10.22489/CinC.2016.051-263</a>
Alternative languages
Result language
angličtina
Original language name
Biventricular pacing optimization by means of the dyssynchrony parameter
Original language description
To improve Cardiac Resynchronization Therapy (CRT), different interventricular delay (VVD) settings can be used. However, relatively small VVD induced hemodynamic changes cannot be measured by standard echocardiographic methods. The QRS complex duration (QRSd) is mostly the main criterion. Here we introduce a new dyssynchrony parameter (DYS) that is able to more accurately detect improved electrical synchrony. Methods: 12-lead 5 kHz ECG during 3-10 minute rest period was measured in 46 patients with CRT OFF and CRT ON with VVD 0 ms (CRT0) and -20 ms (CRT20). We detected QRSd and the dyssynchrony parameter DYS as the time difference between 500-1000 Hz averaged envelopes positions in the V1 and V6 leads in the QRS complex region. Results: 32 of 46 patients had a positive CRT response manifested by QRSd shortening and a DYS decrease. 28 of 32 patients had a positive LV pre-excitation effect: additional QRSd shortening of 4.7+/-.9 ms and a DYS decrease of 12.6+/-7.5 ms. The correlation coefficient of QRSd and DYS changes (CRT 0 vs CRT 20) was 0.23 and indicates information diversity. The DYS parameter differs from QRSd and provides a significantly higher response to VVdelay changes (p <, 0.001).
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
20601 - Medical engineering
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Computing in Cardiology (CinC) 2016
ISBN
978-1-5090-0896-4
ISSN
2325-8861
e-ISSN
—
Number of pages
4
Pages from-to
165-168
Publisher name
Computing in Cardiology
Place of publication
Vencouver
Event location
Vencouver
Event date
Sep 11, 2016
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000405710400042