Novel ultra-high-frequency electrocardiogram tool for the description of the ventricular depolarization pattern before and during cardiac resynchronization

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F20%3A00524957" target="_blank" >RIV/68081731:_____/20:00524957 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/20:00072483 RIV/00216224:14110/20:00115332 RIV/00216208:11120/20:43919607 RIV/00216305:26220/20:PU134379 RIV/00064173:_____/20:N0000089

Result on the web

<a href="https://onlinelibrary.wiley.com/doi/epdf/10.1111/jce.14299" target="_blank" >https://onlinelibrary.wiley.com/doi/epdf/10.1111/jce.14299</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/jce.14299" target="_blank" >10.1111/jce.14299</a>

Result language

angličtina

Original language name

Novel ultra-high-frequency electrocardiogram tool for the description of the ventricular depolarization pattern before and during cardiac resynchronization

Original language description

Introduction The present study introduces a new ultra-high-frequency 14-lead electrocardiogram technique (UHF-ECG) for mapping ventricular depolarization patterns and calculation of novel dyssynchrony parameters that may improve the selection of patients and application of cardiac resynchronization therapy (CRT). Methods Components of the ECG in sixteen frequency bands within the 150 to 1000 Hz range were used to create ventricular depolarization maps. The maximum time difference between the UHF QRS complex centers of mass of leads V1 to V8 was defined as ventricular electrical dyssynchrony (e-DYS), and the duration at 50% of peak voltage amplitude in each lead was defined as the duration of local depolarization (Vd). Proof of principle measurements was performed in seven patients with left (left bundle branch block) and four patients with right bundle branch block (right bundle branch block) before and during CRT using biventricular and His-bundle pacing. Results The acquired activation maps reflect the activation sequence under the tested conditions. e-DYS decreased considerably more than QRS duration, during both biventricular pacing (-50% vs8%) and His-bundle pacing (-77% vs13%). While biventricular pacing slightly increased Vd, His-bundle pacing reduced Vd significantly (+11% vs36%), indicating the contribution of the fast conduction system. Optimization of biventricular pacing by adjusting VV-interval showed a decrease of e-DYS from 102 to 36 ms with only a small Vd increase and QRS duration decrease. Conclusions The UHF-ECG technique provides novel information about electrical activation of the ventricles from a standard ECG electrode setup, potentially improving the selection of patients for CRT and application of CRT.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20601 - Medical engineering

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Cardiovascular Electrophysiology

ISSN

1045-3873

e-ISSN

—

Volume of the periodical

31

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

300-307

UT code for WoS article

000501187800001

EID of the result in the Scopus database

2-s2.0-85076157131