Oxidative damage by carcinogenic polycyclic aromatic hydrocarbons and organic extracts from urban air particulate matter

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F10%3A00340206" target="_blank" >RIV/68378041:_____/10:00340206 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Oxidative damage by carcinogenic polycyclic aromatic hydrocarbons and organic extracts from urban air particulate matter

Original language description

The role of oxidative damage in the mechanisms of action of selected individual c-PAHs, an artificial mixture of c-PAHs and extractable organic matter (EOM) from urban air particulate matter was investigated using two cell lines (HepG2 and HEL). The response of the cell lines to the tested compounds differed substantially. The study demonstrated the potency of EOM to induce oxidative damage to DNA, lipids and proteins in HepG2 cells, but not in HEL cels. The analysis also showed that c-PAHs had less ability to cause oxidative damage.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

DN - Environmental impact on health

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

ISSN

1383-5718

e-ISSN

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Volume of the periodical

696

Issue of the periodical within the volume

2

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

8

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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