The Effect of Distinct Immunosuppressive Drugs on the Phenotype, Metabolic Activity and Apoptosis of Adipose Tissue - Derived Mesenchymal Stem Cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F18%3A00500076" target="_blank" >RIV/68378041:_____/18:00500076 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The Effect of Distinct Immunosuppressive Drugs on the Phenotype, Metabolic Activity and Apoptosis of Adipose Tissue - Derived Mesenchymal Stem Cells
Original language description
A lot of cell-based experimental and clinical protocols include application of Mesenchymal stem cells (MSCs) in combination with immunosuppressive agents. This approach combining MSCs with immunosuppressive agents could enable increase in efficacy of these drugs and thus the reduction of their established therapeutic doses. We demonstrated, that low doses of Cyclosporine A, Mycophenolate mofetil and Rapamycin have no significant adverse effect on cell size, granularity, the expression of surface markers, metabolic activity, apoptosis or cell death of MSCs.
Czech name
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Czech description
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Project
<a href="/en/project/LO1309" target="_blank" >LO1309: Cell Therapy and Tissue Repair</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
Nanostructures in Biomedicine: Their Regenerative and toxic properties
ISBN
978-80-906655-7-6
Number of pages of the result
5
Pages from-to
99-103
Number of pages of the book
198
Publisher name
Proxima Tisk, s.r.o.
Place of publication
Praha 3
UT code for WoS chapter
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