Testing of fibrous membranes with different scaffold morphology for development of 3D skin model

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F20%3A00539919" target="_blank" >RIV/68378041:_____/20:00539919 - isvavai.cz</a>

Alternative codes found

RIV/68407700:21720/20:00348492

Result on the web

<a href="https://www.scientific.net/KEM.834.148" target="_blank" >https://www.scientific.net/KEM.834.148</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.4028/www.scientific.net/KEM.834.148" target="_blank" >10.4028/www.scientific.net/KEM.834.148</a>

Result language

angličtina

Original language name

Testing of fibrous membranes with different scaffold morphology for development of 3D skin model

Original language description

Replacement of in vivo testing using advanced 3D constructs is an important challenge in tissue engineering applications. The cell culture material should be biocompatible and should mimic the natural microenvironment of the existing tissue. Nanofibrous scaffolds prepared by electrospinning from biocompatible polymers have suitable properties for cell culture in a 3D environment. Thanks to the high volume-to-surface ratio, controlled porous structure with high pore interconnection and microarchitecture in the nanoscale range, nanofibers are in the foreground of interest. We tested membranes with different topography with keratinocyte and fibroblast cell lines. Fibroblast showed stable growth with no difference among the scaffolds. On the other hand, keratinocytes preferred scaffolds with nanofiber morphology. © 2020 Trans Tech Publications Ltd, Switzerland.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

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OECD FORD branch

30404 - Biomaterials (as related to medical implants, devices, sensors)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Key Engineering Materials

ISBN

978-303571519-4

ISSN

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e-ISSN

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Number of pages

7

Pages from-to

148-154

Publisher name

Scientific

Place of publication

Bäch

Event location

Salt Lake City

Event date

Aug 2, 2019

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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