Cilia at the crossroad: convergence of regulatory mechanisms to govern cilia dynamics during cell signaling and the cell cycle
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378050%3A_____%2F25%3A00636667" target="_blank" >RIV/68378050:_____/25:00636667 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14110/25:00144366
Result on the web
<a href="https://doi.org/10.1186/s13578-025-01403-z" target="_blank" >https://doi.org/10.1186/s13578-025-01403-z</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s13578-025-01403-z" target="_blank" >10.1186/s13578-025-01403-z</a>
Alternative languages
Result language
angličtina
Original language name
Cilia at the crossroad: convergence of regulatory mechanisms to govern cilia dynamics during cell signaling and the cell cycle
Original language description
Cilia are versatile, microtubule-based organelles that facilitate cellular signaling, motility, and environmental sensing in eukaryotic cells. These dynamic structures act as hubs for key developmental signaling pathways, while their assembly and disassembly are intricately regulated along cell cycle transitions. Recent findings show that factors regulating ciliogenesis and cilia dynamics often integrate their roles across other cellular processes, including cell cycle regulation, cytoskeletal organization, and intracellular trafficking, ensuring multilevel crosstalk of mechanisms controlling organogenesis. Disruptions in these shared regulators lead to broad defects associated with both ciliopathies and cancer. This review explores the crosstalk of regulatory mechanisms governing cilia assembly, disassembly, and maintenance during ciliary signaling and the cell cycle, along with the broader implications for development, tissue homeostasis, and disease.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10601 - Cell biology
Result continuities
Project
<a href="/en/project/GA21-21612S" target="_blank" >GA21-21612S: Interplay between the regulations of cell cycle and ciliogenesis</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Cell and Bioscience
ISSN
2045-3701
e-ISSN
2045-3701
Volume of the periodical
15
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
25
Pages from-to
81
UT code for WoS article
001503494400001
EID of the result in the Scopus database
2-s2.0-105007536809