Study of the Interaction of ligands with adenosine receptors in silico
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F12%3A00184855" target="_blank" >RIV/68407700:21460/12:00184855 - isvavai.cz</a>
Result on the web
<a href="https://www.morebooks.de/store/gb/book/%D0%98%D0%B7%D1%83%D1%87%D0%B5%D0%BD%D0%B8%D0%B5-%D0%B2%D0%B7%D0%B0%D0%B8%D0%BC%D0%BE%D0%B4%D0%B5%D0%B9%D1%81%D1%82%D0%B2%D0%B8%D1%8F-%D0%BB%D0%B8%D0%B3%D0%B0%D0%BD%D0%B4%D0%BE%D0%B2-%D1%81-%D0%B0%D0%B4%D0%B5%D0%BD%" target="_blank" >https://www.morebooks.de/store/gb/book/%D0%98%D0%B7%D1%83%D1%87%D0%B5%D0%BD%D0%B8%D0%B5-%D0%B2%D0%B7%D0%B0%D0%B8%D0%BC%D0%BE%D0%B4%D0%B5%D0%B9%D1%81%D1%82%D0%B2%D0%B8%D1%8F-%D0%BB%D0%B8%D0%B3%D0%B0%D0%BD%D0%B4%D0%BE%D0%B2-%D1%81-%D0%B0%D0%B4%D0%B5%D0%BD%</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
ruština
Original language name
Izuchenie vzaimodejstvija ligandov s adenozinovymi receptorami in silico
Original language description
Adenozinovyjj receptor tipa A2B ehkspressiruetsja mnogimi immunnymi kletkami i oposreduet raz- vitie i podderzhanie khronicheskogo vospalenija pri bronkhial'nojj astme. V svjazi s ehtim adenozinovyjj receptor tipa A2B rassmatrivaetsja kak mishen' v terapii bol'nykh s nekotorymi zabolevanijami leg- kikh. Dlja analiza osobennostejj vzaimodejjstvija molekuly dannogo receptora s molekulami razlichnykh aktivatorov i ingibitorov primenjalos' komp'juternoe modelirovanie. Sozdany modeli adenozinovogo receptoratipa A2B i dvukh ego mutantnykh form (programma Modeller), a takzhe 9 aktivatorov i 15 ingibitorov dannogo receptora (programma ChemSketch). Na osnovanii poluchennykh modelejj proiz- veden raschet ligand-receptornykh vzaimodejjstvijj s ispol'zovaniem programmy AutoDock 4.0. Ustanov- lena predraspolozhennost' vzaimodejjstvija aktivatorov i ingibitorov s opredelennymi aminokislotami ligand-svjazyvajushhego centra adenozinovogo receptora tipa A2B.
Czech name
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Czech description
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Classification
Type
B - Specialist book
CEP classification
IN - Informatics
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
ISBN
978-3-8433-6400-3
Number of pages
100
Publisher name
Lambert Academic Publishing
Place of publication
Saarbrücken
UT code for WoS book
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