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Study of the Interaction of ligands with adenosine receptors in silico

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F12%3A00184855" target="_blank" >RIV/68407700:21460/12:00184855 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.morebooks.de/store/gb/book/%D0%98%D0%B7%D1%83%D1%87%D0%B5%D0%BD%D0%B8%D0%B5-%D0%B2%D0%B7%D0%B0%D0%B8%D0%BC%D0%BE%D0%B4%D0%B5%D0%B9%D1%81%D1%82%D0%B2%D0%B8%D1%8F-%D0%BB%D0%B8%D0%B3%D0%B0%D0%BD%D0%B4%D0%BE%D0%B2-%D1%81-%D0%B0%D0%B4%D0%B5%D0%BD%" target="_blank" >https://www.morebooks.de/store/gb/book/%D0%98%D0%B7%D1%83%D1%87%D0%B5%D0%BD%D0%B8%D0%B5-%D0%B2%D0%B7%D0%B0%D0%B8%D0%BC%D0%BE%D0%B4%D0%B5%D0%B9%D1%81%D1%82%D0%B2%D0%B8%D1%8F-%D0%BB%D0%B8%D0%B3%D0%B0%D0%BD%D0%B4%D0%BE%D0%B2-%D1%81-%D0%B0%D0%B4%D0%B5%D0%BD%</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    ruština

  • Original language name

    Izuchenie vzaimodejstvija ligandov s adenozinovymi receptorami in silico

  • Original language description

    Adenozinovyjj receptor tipa A2B ehkspressiruetsja mnogimi immunnymi kletkami i oposreduet raz- vitie i podderzhanie khronicheskogo vospalenija pri bronkhial'nojj astme. V svjazi s ehtim adenozinovyjj receptor tipa A2B rassmatrivaetsja kak mishen' v terapii bol'nykh s nekotorymi zabolevanijami leg- kikh. Dlja analiza osobennostejj vzaimodejjstvija molekuly dannogo receptora s molekulami razlichnykh aktivatorov i ingibitorov primenjalos' komp'juternoe modelirovanie. Sozdany modeli adenozinovogo receptoratipa A2B i dvukh ego mutantnykh form (programma Modeller), a takzhe 9 aktivatorov i 15 ingibitorov dannogo receptora (programma ChemSketch). Na osnovanii poluchennykh modelejj proiz- veden raschet ligand-receptornykh vzaimodejjstvijj s ispol'zovaniem programmy AutoDock 4.0. Ustanov- lena predraspolozhennost' vzaimodejjstvija aktivatorov i ingibitorov s opredelennymi aminokislotami ligand-svjazyvajushhego centra adenozinovogo receptora tipa A2B.

  • Czech name

  • Czech description

Classification

  • Type

    B - Specialist book

  • CEP classification

    IN - Informatics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • ISBN

    978-3-8433-6400-3

  • Number of pages

    100

  • Publisher name

    Lambert Academic Publishing

  • Place of publication

    Saarbrücken

  • UT code for WoS book