Continuous Distending Pressure Effects on Variables Contributing to Oxygenation in Healthy and ARDS Model Pigs during HFOV
The result's identifiers
Result code in IS VaVaI
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Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Continuous Distending Pressure Effects on Variables Contributing to Oxygenation in Healthy and ARDS Model Pigs during HFOV
Original language description
The aim of this study is to evaluate effects of continuous distending pressure (CDP) on variables that contribute to the oxygenation in healthy and ARDS lung model pigs. Methods. In order to simulate a lung disease, lung injury was induced by lavage withnormal saline with detergent in three pigs. HFOV ventilation was applied before and after the lung lavage. CDP was stepwise increased by 2 cmH(2)O, until the maximum CDP (before the lung lavage 32 cmH(2)O and after the lung lavage 42 cmH(2)O) and then it was stepwise decreased by 2 cmH(2)O to the initial value. In this paper we analyzed the following parameters acquired during our experiments: partial pressure of oxygen in arterial blood (PaO2), cardiac output (CO) and mixed venous blood oxygen saturation (SvO(2)). In order to find how both Pat), and CO affected SvO(2) during the increase of CDP before and after lavage, a nonlinear regression fitting of the response in SvO(2) on the predictors (PaO2 and CO) was implemented. Results. Be
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
BJ - Thermodynamics
OECD FORD branch
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Result continuities
Project
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Continuities
O - Projekt operacniho programu
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
International Conference of Computational Methods in Sciences and Engineering 2014 (ICCMSE)
ISBN
978-0-7354-1255-2
ISSN
0094-243X
e-ISSN
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Number of pages
5
Pages from-to
962-966
Publisher name
American Institute of Physics
Place of publication
Melville, New York
Event location
Athens
Event date
Apr 4, 2014
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000346015200204