Pneumatic Driven Pulsatile Perfusion Bioreactor for Tissue Enginered Vascular Replacements

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21460%2F24%3A00371295" target="_blank" >RIV/68407700:21460/24:00371295 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-3-031-62520-6_43" target="_blank" >http://dx.doi.org/10.1007/978-3-031-62520-6_43</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-3-031-62520-6_43" target="_blank" >10.1007/978-3-031-62520-6_43</a>

Result language
angličtina
Original language name
Pneumatic Driven Pulsatile Perfusion Bioreactor for Tissue Enginered Vascular Replacements
Original language description
Shear stress simulated in the bioreactor has a positive effect on the modulation of endothelial cells, their grow and gene expression. The aim of this work is to design and characterize a pressure wave-controlled perfusion system for stimulating both planar and tubular tissue in the culture chamber. This system must be able to deliver both small and large flow rates. Designed circuit consists of two large volume cartridges that alternately filled with culture medium. The flow direction is controlled by 3-way valves which are controlled by servo motors. The flow reading is based on the differential intensity of the LEDs through the filled and empty syringe. Servo motor control and signal processing from the photodiodes was realized on the Arduino platform. The assembled circuit was tested in a laboratory environment and subsequently used in a culture experiment with immortalized cells of the mouse endothelial line MS-1.
Czech name
—
Czech description
—

Project
<a href="/en/project/NV19-02-00068" target="_blank" >NV19-02-00068: Bioartificial cardiovascular patches and vessels from porcine collagen reinforced with nano/microfibers using stem cells and dynamic culture</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Advances in Digital Health and Medical Bioengineering, Proceedings of the 11th International Conference on E-Health and Bioengineering, EHB-2023, November 9–10, 2023, Bucharest, Romania – Volume 2: Health Technology Assessment, Biomedical Signal Processing, Medicine and Informatics
ISBN
978-3-031-62519-0
ISSN
1680-0737
e-ISSN
1433-9277
Number of pages
9
Pages from-to
388-396
Publisher name
Springer Nature Switzerland AG
Place of publication
Basel
Event location
Bucuresti
Event date
Nov 9, 2023
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
001326809000043

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