Factors influencing encapsulation efficiency of biologically active compound into PLA submikroparticles
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F70883521%3A28110%2F11%3A43866050" target="_blank" >RIV/70883521:28110/11:43866050 - isvavai.cz</a>
Alternative codes found
RIV/70883521:28610/11:43866050
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Factors influencing encapsulation efficiency of biologically active compound into PLA submikroparticles
Original language description
The low molecular weight biodegradable poly(lactide acid) (PLA) was tested as suitable material for encapsulation of bioactive agent into microparticles by the method of emulsification and solvent evaporation at reduced pressure. The attention was focused on the examination of encapsulation capacity for incorporation of a model herbicide. The initial amount of herbicide was altered and parameters characterizing microparticles like encapsulation efficiency, size and shape were evaluated by different methods. Low molecular PLA proved to be a suitable matrix for easy encapsulation of bioactive compounds by the oil-in-water emulsion solvent evaporation method, furthermore without significant changes in particles size. The relative lowest loss of herbicidealong with the highest encapsulation efficiency was achieved for the highest initial concentration of herbicide which is close to the critical concentration under which the particles could still be prepared.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
EE - Microbiology, virology
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Recent Researches in Geography, Geology, Energy, Environment and Biomedicine - Proc. of the 4th WSEAS Int. Conf. on EMESEG'11, 2nd Int. Conf. on WORLD-GEO'11, 5th Int. Conf. on EDEB'11
ISBN
978-1-61804-022-0
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
170-175
Publisher name
WSEAS Press (GR)
Place of publication
Rhodes
Event location
Corfu Island
Event date
Jul 14, 2011
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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