Funkce a dynamika telomér v rostlinné meióze

Název projektu anglicky
A means to the ends - analysis of telomere function and dynamics in plant meiosis
Anotace anglicky
Chromosome recombination and their assortment during meiosis are key mechanisms for generating genetic diversity in eukaryotic organisms. Faithful segregation of homologous chromosomes requires their pairing and synapsis in meiotic prophase I. Telomeres seem to play an important role in chromosome pairing. They form so called telomere bouquet and were shown to drive rapid chromosome movements that facilitates pairing. We know only very little about this process and its molecular underpinning in plants. Here we will take advantage of our combine expertise in telomere biology and live imaging of meiosis to generate markers for in vivo labeling of telomeres and use them to perform detailed spatiotemporal analysis of telomere dynamics and chromosome movements in Arabidopsis thaliana. We will directly assess the role of telomeres in meiosis by using a unique line that harbors extremely short telomeres. In addition, we will identify components of the plant sheltering complex, which will pave way for future deciphering of molecular machinery underlying chromosome pairing in plants.

Kategorie VaV
ZV - Základní výzkum
OECD FORD - hlavní obor
10601 - Cell biology
OECD FORD - vedlejší obor
10603 - Genetics and heredity (medical genetics to be 3)
OECD FORD - další vedlejší obor
10611 - Plant sciences, botany
CEP - odpovídající obory <br>(dle <a href="http://www.vyzkum.cz/storage/att/E6EF7938F0E854BAE520AC119FB22E8D/Prevodnik_oboru_Frascati.pdf">převodníku</a>)
EA - Morfologické obory a cytologie<br>EB - Genetika a molekulární biologie<br>EF - Botanika

Důvěrnost údajů
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Systémové označení dodávky dat
CEP25-GA0-GC-R
Datum dodání záznamu
12. 3. 2025

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