Complex analysis of counterfeit medicinal drugs and new synthetic drugs (novel psychoactive substances) in forensic practice

Kód výsledku v IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F00007064%3AK01__%2F22%3AN0000100" target="_blank" >RIV/00007064:K01__/22:N0000100 - isvavai.cz</a>

Výsledek na webu

<a href="https://www.epdic17.org/" target="_blank" >https://www.epdic17.org/</a>

DOI - Digital Object Identifier

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Jazyk výsledku

angličtina

Název v původním jazyce

Complex analysis of counterfeit medicinal drugs and new synthetic drugs (novel psychoactive substances) in forensic practice

Popis výsledku v původním jazyce

2 stránkový článek ve sborníku - Book of abstracts, EPDIC17 Kotrlý M., Turková I.: Complex analysis of counterfeit medicinal drugs and new synthetic drugs (novel psychoactive substances) in forensic practice. Book of abstracts, EPDIC17, p. 142-143, Šibenik, 2022 abstract of the article:: Counterfeit medicinal drugs represent a massive danger to patients. They might not contain an active substances, a wrong or incorrect concentration, harmful or even poisonous components. The consequences are lower treatment effectiveness or even death. Number of the fakes has risen worldwide in the last years. According to the World Health Organization (WHO) the value of the world fake medicinal drugs market is around 200 billion dollars a year making it the most profitable trade with illegally copied goods. WHO estimates that at least a half of all medicinal drugs sold today in e-shops, which hide their real address, is counterfeit. Forensic analysis deals with these materials comprehensively. Characterization of the pills surface is carried out through methods of optical and electron microscopy and is compared with original products. Imprints (embossing) and the logo placement are compared using comparative methods of image analysis. Inner structure of the tablet, thickness of packaging layer, etc. are studied by means of electron microscopy. Microspectrophotometric measurement of product colours is performed and compared with the original in some cases. X-ray diffraction is used for a full phase analysis; it is possible to carry out an analysis directly from a tablet surface not causing any damage to it and the recording allows identification of all phases. In practice, a non-destructive analysis of tablets is carried out directly in blister packs. Within the experiment, 7 types of foils of different thickness were tested – PVC, PVD, PVPC, PE, ACLAR (fluoropolymer). It was found out that even if the diffraction signal is weakened, the recording is fully identifiable even under standard parameters. If necessary, signal acquisition time can be extended.

Název v anglickém jazyce

Complex analysis of counterfeit medicinal drugs and new synthetic drugs (novel psychoactive substances) in forensic practice

Popis výsledku anglicky

2 stránkový článek ve sborníku - Book of abstracts, EPDIC17 Kotrlý M., Turková I.: Complex analysis of counterfeit medicinal drugs and new synthetic drugs (novel psychoactive substances) in forensic practice. Book of abstracts, EPDIC17, p. 142-143, Šibenik, 2022 abstract of the article:: Counterfeit medicinal drugs represent a massive danger to patients. They might not contain an active substances, a wrong or incorrect concentration, harmful or even poisonous components. The consequences are lower treatment effectiveness or even death. Number of the fakes has risen worldwide in the last years. According to the World Health Organization (WHO) the value of the world fake medicinal drugs market is around 200 billion dollars a year making it the most profitable trade with illegally copied goods. WHO estimates that at least a half of all medicinal drugs sold today in e-shops, which hide their real address, is counterfeit. Forensic analysis deals with these materials comprehensively. Characterization of the pills surface is carried out through methods of optical and electron microscopy and is compared with original products. Imprints (embossing) and the logo placement are compared using comparative methods of image analysis. Inner structure of the tablet, thickness of packaging layer, etc. are studied by means of electron microscopy. Microspectrophotometric measurement of product colours is performed and compared with the original in some cases. X-ray diffraction is used for a full phase analysis; it is possible to carry out an analysis directly from a tablet surface not causing any damage to it and the recording allows identification of all phases. In practice, a non-destructive analysis of tablets is carried out directly in blister packs. Within the experiment, 7 types of foils of different thickness were tested – PVC, PVD, PVPC, PE, ACLAR (fluoropolymer). It was found out that even if the diffraction signal is weakened, the recording is fully identifiable even under standard parameters. If necessary, signal acquisition time can be extended.

Druh

O - Ostatní výsledky

CEP obor

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OECD FORD obor

50902 - Social sciences, interdisciplinary

Projekt

<a href="/cs/project/VI20152020035" target="_blank" >VI20152020035: Zavedení systému komplexních analýz SEM-automatické analýzy púdních fází a Ramanovy spektroskopie do praxe znalecké služby PČR</a><br>

Návaznosti

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Rok uplatnění

2022

Kód důvěrnosti údajů

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů